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. 2005 Sep 5;202(5):637–650. doi: 10.1084/jem.20050821

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Copyright © 2005, The Rockefeller University Press

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Figure 1. — IFN-IR⁰ P14 CD8 T cells respond normally in vitro. (A) Phenotypic analysis of spleen cells derived from WT P14 TCR transgenic mice and IFN-IR⁰ P14 TCR transgenic mice. Numbers represent the percentage of cells in the indicated quadrant. (B) Spleen cells derived from WT and IFN-IR⁰ P14 TCR transgenic mice were cultured in vitro for 5 h either in the absence or presence of GP33-41 peptide and stained for cytokines. Data are gated on CD8 T cells. Numbers represent the percentage of cells in the indicated quadrant. (C) CFSE-labeled WT and IFN-IR⁰ P14 spleen cells cultured for 3 d with (bottom) and without (top) peptide stimulus. Data are gated on CD8 T cells.