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. 2005 Jul 4;202(1):73–84. doi: 10.1084/jem.20050198

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Copyright © 2005, The Rockefeller University Press

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Figure 2. — The features of psoriasiform dermatitis in MM14.4 transgenic mice. Nontransgenic littermates (a–c) had normal-appearing skin and hair. In contrast, transgenic mice had loss of hair and scaling skin (d–h). c and f are enlarged areas framed in b and e, respectively. Lesions were characterized by thickening of the epidermis and intense scaling, mononuclear infiltrates in the epidermis and dermis, occasional subcorneal pustules (g), and focal parakeratosis (f and h). Epidermal hyperplasia was marked by loss of keratin 1 and 10 (i and j) and acquisition of expression of keratin 6 (k), typical for hyperplasia. Bar, 100 μm.