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. 2005 Sep 19;202(6):761–769. doi: 10.1084/jem.20050193

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Copyright © 2005, The Rockefeller University Press

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Figure 2. — Cytokine mRNA expression following pulmonary K. pneumoniae infection. Animals were administered 10⁴ CFU bacteria and killed at specified time points. BAL cell pellet and lung homogenate mRNA were assayed via real-time RT-PCR. (A) Increases in BAL cell IL-23 p19, IL-12/23 p40, and IL-12 p35 mRNA expression during infection (n = 4–5 per group). (B) Whole lung tissue IL-23 p19, IL-17, and IL-17F mRNA expression following infection (n = 4–5 per group). Data are normalized for 18s ribosomal RNA content and plotted as fold change over baseline (time 0) expression. *Earliest significant (P < 0.05) increase in expression compared with time zero transcripts. Error bars represent mean ± SD.