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. 2005 Dec 19;202(12):1679–1689. doi: 10.1084/jem.20051473

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Copyright © 2005, The Rockefeller University Press

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Figure 5. — Tumor metastasis in NK cell-depleted Rag-1 ^−/− mice. (A and B) See Fig. 4 for details. The development of tumor foci in control IgG-treated lymph nodes (A) and anti-NK1.1–treated lymph nodes (B). 6 out of 11 anti-NK1.1–treated and 6 out of 10 control IgG-treated lymph nodes are shown. (C) The number of NK cells and (D) the relative tumor burden in the popliteal lymph nodes bearing B16 tumors. Symbols in C and D represent individual mice. Bars in C and D indicate the median values. p-values are relative to control IgG-treated mice.