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. 1961 Jul;47(7):907–932. doi: 10.1073/pnas.47.7.907

SODIUM-DEPENDENT „TRANSPORT” REACTIONS IN THE CELL NUCLEUS AND THEIR ROLE IN PROTEIN AND NUCLEIC ACID SYNTHESIS*

V G Allfrey 1, R Meudt 1, J W Hopkins 1, A E Mirsky 1
PMCID: PMC221304  PMID: 13682569

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Selected References

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  1. ALLFREY V. G., HOPKINS J. W., FRENSTER J. H., MIRSKY A. E. Reactions governing incorporation of amino acids into the proteins of the isolated cell nucleus. Ann N Y Acad Sci. 1960 Aug 31;88:722–740. doi: 10.1111/j.1749-6632.1960.tb20066.x. [DOI] [PubMed] [Google Scholar]
  2. ALLFREY V. G., MIRSKY A. E., OSAWA S. Mononucleotides of the cell nucleus. J Gen Physiol. 1957 Jan 20;40(3):491–513. [PMC free article] [PubMed] [Google Scholar]
  3. ALLFREY V. G., MIRSKY A. E., OSAWA S. Protein synthesis in isolated cell nuclei. J Gen Physiol. 1957 Jan 20;40(3):451–490. doi: 10.1085/jgp.40.3.451. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. ALLFREY V. G., MIRSKY A. E. On the supposed contamination of thymus nuclear fractions by whole cells. Science. 1955 Jun 17;121(3155):879–880. doi: 10.1126/science.121.3155.879. [DOI] [PubMed] [Google Scholar]
  5. ALLFREY V. G., MIRSKY A. E. Protein synthesis in isolated cell nuclei. Nature. 1955 Dec 3;176(4492):1042–1049. doi: 10.1038/1761042a0. [DOI] [PubMed] [Google Scholar]
  6. ALLFREY V., STERN H., MIRSKY A. E., SAETREN H. The isolation of cell nuclei in non-aqueous media. J Gen Physiol. 1952 Jan;35(3):529–554. doi: 10.1085/jgp.35.3.529. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Allfrey V. G. AMINO ACID INCORPORATION BY ISOLATED THYMUS NUCLEI. I. THE ROLE OF DESOXYRIBONUCLEIC ACID IN PROTEIN SYNTHESIS. Proc Natl Acad Sci U S A. 1954 Oct;40(10):881–885. doi: 10.1073/pnas.40.10.881. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Allfrey V. G., Mirsky A. E. SOME ASPECTS OF RIBONUCLEIC ACID SYNTHESIS IN ISOLATED CELL NUCLEI. Proc Natl Acad Sci U S A. 1957 Sep 15;43(9):821–826. doi: 10.1073/pnas.43.9.821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Allfrey V. G., Mirsky A. E. SOME ASPECTS OF RIBONUCLEIC ACID SYNTHESIS IN ISOLATED CELL NUCLEI. Proc Natl Acad Sci U S A. 1957 Sep 15;43(9):821–826. doi: 10.1073/pnas.43.9.821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. BATTAGLIA F. C., MANCHESTER K. L., RANDLE P. J. Effects of insulin on monosaccharide transport and incorporation of amino acids into protein in diaphragm differentiated with phlorizin. Biochim Biophys Acta. 1960 Sep 9;43:50–54. doi: 10.1016/0006-3002(60)90405-4. [DOI] [PubMed] [Google Scholar]
  11. BREITMAN T. R., WEBSTER G. C. Assimilation of nucleic acid precursors by isolated thymus nuclei. Exp Cell Res. 1959 Oct;18:413–414. doi: 10.1016/0014-4827(59)90030-8. [DOI] [PubMed] [Google Scholar]
  12. BREITMAN T. R., WEBSTER G. C. Mon valent cations and the incorporation of metabolites by isolated thymus nuclei. Nature. 1959 Aug 22;184(Suppl 9):637–638. doi: 10.1038/184637a0. [DOI] [PubMed] [Google Scholar]
  13. Britten R. J., Roberts R. B., French E. F. AMINO ACID ADSORPTION AND PROTEIN SYNTHESIS IN Escherichia Coli. Proc Natl Acad Sci U S A. 1955 Nov 15;41(11):863–870. doi: 10.1073/pnas.41.11.863. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. CHRISTENSEN H. N., RIGGS T. R. Concentrative uptake of amino acids by the Ehrlich mouse ascites carcinoma cell. J Biol Chem. 1952 Jan;194(1):57–68. [PubMed] [Google Scholar]
  15. CRANE R. K., LIPMANN F. The effect of arsenate on aerobic phosphorylation. J Biol Chem. 1953 Mar;201(1):235–243. [PubMed] [Google Scholar]
  16. DALY M. M., MIRSKY A. E. Histones with high lysine content. J Gen Physiol. 1955 Jan 20;38(3):405–413. doi: 10.1085/jgp.38.3.405. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. FICQ A., ERRERA M. Analyse autoradiographique de l'incorporation de la phénylalanine-2-14C dans les noyaux isolés. Exp Cell Res. 1958 Feb;14(1):182–192. doi: 10.1016/0014-4827(58)90225-8. [DOI] [PubMed] [Google Scholar]
  18. FRENSTER J. H., ALLFREY V. G., MIRSKY A. E. In vitro incorporation of amino acids into the proteins of isolated nuclear ribosomes. Biochim Biophys Acta. 1961 Feb 12;47:130–137. doi: 10.1016/0006-3002(61)90837-x. [DOI] [PubMed] [Google Scholar]
  19. FRIEDKIN M., WOOD H. I. V. Utilization of thymidine-C14 by bone marrow cells and isolated thymus nuclei. J Biol Chem. 1956 Jun;220(2):639–651. [PubMed] [Google Scholar]
  20. Frenster J. H., Allfrey V. G., Mirsky A. E. METABOLISM AND MORPHOLOGY OF RIBONUCLEOPROTEIN PARTICLES FROM THE CELL NUCLEUS OF LYMPHOCYTES. Proc Natl Acad Sci U S A. 1960 Apr;46(4):432–444. doi: 10.1073/pnas.46.4.432. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. GUILLAUME J., DERIEUX J. C., OSTEUX R. [On the bactericidal action of histones. Modifications of cellular permeability]. C R Hebd Seances Acad Sci. 1961 Feb 13;252:1070–1072. [PubMed] [Google Scholar]
  22. HOAGLAND M. B. An enzymic mechanism for amino acid activation in animal tissues. Biochim Biophys Acta. 1955 Feb;16(2):288–289. doi: 10.1016/0006-3002(55)90218-3. [DOI] [PubMed] [Google Scholar]
  23. HOLTER H., MOLLER K. M. A substance for aqueous density gradients. Exp Cell Res. 1958 Dec;15(3):631–632. doi: 10.1016/0014-4827(58)90116-2. [DOI] [PubMed] [Google Scholar]
  24. HOPKINS J. W., ALLFREY V. G., MIRSKY A. E. A denosine as the receptor end group in nuclear amino acid-transfer RNA. Biochim Biophys Acta. 1961 Feb 12;47:194–196. doi: 10.1016/0006-3002(61)90851-4. [DOI] [PubMed] [Google Scholar]
  25. Hopkins J. W. AMINO ACID ACTIVATION AND TRANSFER TO RIBONUCLEIC ACIDS IN THE CELL NUCLEUS. Proc Natl Acad Sci U S A. 1959 Oct;45(10):1461–1470. doi: 10.1073/pnas.45.10.1461. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. ITOH S., SCHWARTZ I. L. Sodium and potassium distribution in isolated thymus nuclei. Am J Physiol. 1957 Mar;188(3):490–498. doi: 10.1152/ajplegacy.1957.188.3.490. [DOI] [PubMed] [Google Scholar]
  27. KELLER E. B., ZAMECNIK P. C. The effect of guanosine diphosphate and triphosphate on the incorporation of labeled amino acids into proteins. J Biol Chem. 1956 Jul;221(1):45–59. [PubMed] [Google Scholar]
  28. LORENTE DE NO R., VIDAL F., LARRAMENDI L. M. Restoration of sodium-deficient frog nerve fibres by onium ions. Nature. 1957 Apr 6;179(4562):737–738. doi: 10.1038/179737b0. [DOI] [PubMed] [Google Scholar]
  29. MONOD J., COHN M. La biosynthèse induite des enzymes; adaptation enzymatique. Adv Enzymol Relat Subj Biochem. 1952;13:67–119. [PubMed] [Google Scholar]
  30. PALADE G. E. Studies on the endoplasmic reticulum. II. Simple dispositions in cells in situ. J Biophys Biochem Cytol. 1955 Nov 25;1(6):567–582. doi: 10.1083/jcb.1.6.567. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. RIGGS T. R., WALKER L. M., CHRISTENSEN H. N. Potassium migration and amino acid transport. J Biol Chem. 1958 Dec;233(6):1479–1484. [PubMed] [Google Scholar]
  32. ROBBINS E. The rate of proflavin passage into single living cells with application to permeability studies. J Gen Physiol. 1960 Mar;43:853–866. doi: 10.1085/jgp.43.4.853. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. SACHS H. A stabilized enzyme system for amino acid incorporation. J Biol Chem. 1957 Sep;228(1):23–39. [PubMed] [Google Scholar]
  34. SCHWEITZER G. K., STEIN B. R. Measuring solid samples of low-energy beta emitters. Nucleonics. 1950 Sep;7(3):65–72. [PubMed] [Google Scholar]
  35. SIMMEL E. B. The use of a fast, coarse-grain stripping film for radioautography. Stain Technol. 1957 Nov;32(6):299–300. doi: 10.3109/10520295709111644. [DOI] [PubMed] [Google Scholar]
  36. STERN H., MIRSKY A. E. Soluble enzymes of nuclei isolated in sucrose and nonaqueous media; a comparative study. J Gen Physiol. 1953 Nov 20;37(2):177–187. doi: 10.1085/jgp.37.2.177. [DOI] [PMC free article] [PubMed] [Google Scholar]

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