Table I.
Subject characteristics
| Asthma (ICSs treated) | Asthma (ICSs naive) | Healthy controls | p-value | |
|---|---|---|---|---|
| Number | 14 | 10 | 10 | NA |
| Sex (percent male) | 69% | 60% | 60% | P = 0.8 |
| Mean age (range) | 32 (21–58) | 32 (12.6) | 29 (24–38) | P = 0.4 |
| Mean FEV1% predicted (SD) | 77.3a (15.5) | 103.6 (9.8) | 110.3 (13.6) | P < 0.001 |
| Mean dose of ICSs, BDP μg/day (SD) | 490 (260) | 0 | 0 | NA |
FEV1% predicted refers to the forced expiratory volume in 1 s expressed as a percentage of the predicted value.
ICSs refers to ICSs. Dose is expressed in dose of beclomethasone dipropionate (BDP) in μg per day where 1 μg BDP = 1 μg Budesonide or 0.5 μg Fluticasone.
aSignificantly lower than healthy controls, P < 0.001.