Table II.
Expression of different receptors on NK cells from single MHC class I mice
Receptors
|
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---|---|---|---|---|---|---|---|---|
Mouse | NK1.1 | CD11b | NKG2D | CD16 | 2B4 | Ly49D | KLRG1 | |
Percent1 | Db | 3.6 (0.5) | 80 (7) | 91 (3) | 97 (3) | 93 (3) | 48 (4) | 48 (9)2 |
Ld | 3.3 (0.8) | 77 (10) | 90 (4) | 93 (6) | 85 (3) | 49 (11) | 58 (8)3 | |
Kb | 3.2 (0.8) | 76 (10) | 92 (3) | 97 (3) | 92 (5) | 47 (5) | 51 (9)2 | |
Dd | 2.9 (0.8) | 78 (7) | 93 (2) | 97 (3) | 92 (2) | 46 (3) | 63 (5)2 | |
MHC− | 3.9 (1.1) | 74 (7) | 91 (2) | 92 (8) | 92 (3) | 37 (7) | 37 (11) | |
MFI4 | Db | 111 (14) | 117 (23) | 100 (12) | 156 (44) | 129 (30)2 | 97 (10) | 133 (4) |
Ld | 114 (8) | 125 (24) | 102 (14) | 102 (31) | 129 (44) | 78 (8)3 | 153 (9)2 | |
Kb | 101 (15) | 99 (15) | 109 (23) | 139 (44) | 116 (24) | 100 (8) | 152 (28)3 | |
Dd | 101 (20) | 107 (30) | 108 (17) | 138 (36) | 127 (41) | 90 (8)2 | 171 (18)3 |
Percentage of NK1.1+CD3− cells, except for NK1.1, that shows percentage of NK1.1+CD3− cells in whole spleen. Numbers in parentheses indicate SD.
P < 0.05 compared with MHC− mice.
P < 0.01 compared with MHC− mice.
Mean fluorescence intensity in percentage of MHC− mice. Numbers in parentheses indicate SD.