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. 2005 Apr 4;201(7):1145–1155. doi: 10.1084/jem.20050167

Table III.

Frequencies of Ly49 and NKG2A receptors in single MHC class I mice

Receptor 1 Frequency of
receptor2 		NK cells withdown-regulatedLy49 3 NK cells with
down-regulated
Ly49 or NKG2A4 		DRI5 Weighted sum
of DRI6
% %
Db mouse 46 68 8.5
Ly49G2 55 7.7
Ly49A 16 13.8
Ly49F 11 7.2
Ly49C 36 17.4
Ly49I 58 −0.1
NKG2A 40 N/A
Ld mouse 63 80 18.8
Ly49G2 55 23.2
Ly49A 11 41.5
Ly49F 9 16.9
Ly49C 34 13.0
Ly49I 59 −7.3
NKG2A 46 N/A
Kb mouse 38 38 33.4
Ly49G2 47 −0.2
Ly49A 18 8.6
Ly49F 8 −3.0
Ly49C 38 88.0
Ly49I 47 −9.6
NKG2A 48 N/A
Dd mouse 75 84 29.8
Ly49G2 49 21.9
Ly49A 17 57.5
Ly49F 9 10.4
Ly49C 36 23.4
Ly49I 54 −0.9
NKG2A 38 N/A
1

Significantly down-regulated Ly49 receptors are in bold (see Fig. 5).

2

Frequencies include all NK cells expressing the receptor, irrespective of any overlap with other receptors.

3

The percentage of NK cells expressing any Ly49 receptor was calculated using the product rule to exclude counting NK cells expressing more than one Ly49 receptor twice. Only cells expressing a significantly down-regulated Ly49 receptors (bold) were included.

4

The percentage of NK cells expressing either any down-regulated Ly49 receptor or NKG2A. NKG2A+ NK cells were included only when the ligand is present in the host (e.g., in Db, Ld, and Dd single mice).

5

The DRI denotes the level of receptor down-regulation compared with the MHC− mouse in percentage of mean fluorescence intensity.

6

The weighted sum of DRI is the sum of individual DRI from significantly down-regulated Ly49 receptors (bold) multiplied by the indicated frequency of this receptor. The frequencies include all cells expressing the receptor, irrespective of any overlap with other receptors.