Figure 1.

The signaling domains of short-tailed hominoid KIR form a monophyletic group within lineage III KIR. (A) Comparison of mammalian KIR signaling domains shows that primate sequences form a monophyletic group. To simplify the tree, the primate sequences were collapsed. (B) Among primate KIR the signaling domains of short-tailed KIR form a monophyletic group within lineage III (B). Neighbor joining (NJ) and Bayesian trees gave statistically similar topologies; the NJ topology is displayed (using a midpoint rooting). Colored boxes denote the different KIR lineages. The statistical support for each node (expressed as a percentage) was given by the interior branch test confidence probability and the Bayesian posterior probability. Values are shown for nodes supported by ≥90% with one or both methods; asterisks indicate values <90%. Nodes marked by a filled circle were supported ≥95% by both methods. Gg, Gorilla gorilla; Mm, Macaca mulatta; Pt, Pan troglodytes; Pp, Pan paniscus, Popy, Pongo pygmaeus.