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. 2005 Oct 17;202(8):1051–1061. doi: 10.1084/jem.20040662

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Copyright © 2005, The Rockefeller University Press

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Figure 2. — CD103 is not required for the development of colitis. C.B.-17-SCID mice received 4 × 10⁵ sorted CD4⁺CD45RB^high T cells. At death, hosts were analyzed for various parameters. (A) T cell numbers recovered from various organs. Symbols represent individual mice. Data are pooled from three independent experiments. The horizontal lines represent the mean. (B) Intracytoplasmic cytokine production by T cells from the LP after overnight stimulation with anti-CD3 antibodies. The numbers shown indicate the percentage of cells in that gate. Data are representative of three individual animals per group. (C) Cumulative colitis incidence in various recipients of CD103^−/− CD4⁺CD45RB^high T cells. Data are pooled from seven independent experiments.