Figure 1.

Adherent leukocytes per 200-μm length of vessel (increase above background; A) and percent reduction in leukocyte rolling flux (B) due to injection of 600 ng KC into the carotid artery cannula. Data was acquired 1 min before and after injection into WT (7 venules in 3 mice; white bars), WT plus 4 μg PTx 3 h before cremaster exteriorization (10 venules in 4 mice; light gray bars), E-selectin^−/− (6 venules in 2 mice; dark gray bars), and E-selectin^−/− plus PTx (5 venules in 2 mice; black bars). *, P < 0.05 versus WT control (A) or rolling flux before KC injection (B).