Table I.

Genetic Loci Associated with Hypermucoviscosity in K. pneumoniae

Mutant	Loci	Function	Reference
1–11a	cps cluster	capsular polysaccharide synthesis	37
12	wb cluster	lipopolysaccharide synthesis	38
13b	novel 1.2-kb ORF	identical to mutant 18	–
14	novel 1.6-kb ORF	57-kD hypothetical protein, putative thiosulfate sulfurtransferase	–
15	novel 0.9-kb ORF	33-kD hypothetical protein	–
16c	–	–	–
17	cps cluster ORF 6	80-kD hypothetical protein, function unknown	37
18b	novel 1.2-kb ORF	43-kD hypothetical protein, putative membrane lipoprotein	–
19	novel 1.6-kb ORF	57-kD hypothetical protein, putative phosphotransferase	–
20	rmpA	extracapsular polysaccharide synthesis regulator	39, 40

^aMutants 1–10, gross loss of mucoid phenotype. Mutants 11–20, negative string test.

^bMutants 13 and 18, the same locus was disrupted.

^cMutant 16, it possessed double insertion of transposon and was not further studied.

ORF, open reading frame.