Table 3.

Evaluation of Pulmonary Inflammation of Immunized Mice after RSV Challenge

Immunogen		Bronchioles				Blood Vessels
		No. scored		Mean ± SD		No. scored		Mean ± SD
pXL2 (i.m.)		262		3.10 ± 1.15		390		3.53 ± 1.30
pXL2 (i.d.)		287		2.42 ± 1.25		330		2.54 ± 1.40
RSV (i.n.)		160		3.16 ± 0.96		263		4.39 ± 1.09
FI-RSV (i.m.)		193		2.36 ± 1.08		257		2.62 ± 1.26
pXL0 (i.m.)		157		1.35 ± 0.60		242		1.45 ± 0.87

Mice were immunized and challenged as in Table 2. Lungs were removed 4 d later and fixed with PBS-buffered formalin. Sections from both the left and the right lobes were scored (from 1 to 6) for inflammatory reactions according to Murphy et al. (31).