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. 1998 Oct 19;188(8):1503–1510. doi: 10.1084/jem.188.8.1503

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Localization of B cells is determined by the splenic environment. (A–E) Purified, CFSE-labeled B cells from WT and mutant mice were transferred into WT, TNF^−/−, and TNF/LTα^−/− recipients in combinations as indicated. (G and H) Anti– HEL-Ig Tg B cells were transferred at day 0 intravenously to WT recipients immediately after intraperitoneal injection of 0.5 ml PBS (control) or 200 μg TNFR-Ig in 0.5 ml PBS. Spleen sections were stained 20 h after cell transfer for splenic B cells (red) and transferred B cells (CSFE or HEL-specific Ig; yellow). Bar = 200 μm.