Table 1.

Concentration of HA-biot or Number of HA-biot–MHC Complexes Per Cell Necessary to Induce a Half-maximal Response in T Cells

		B cells				DCs
		Ag concentration		No. of Ag–MHC complexes/B cell		Ag concentration		No. of Ag–MHC complexes/DC
		ng/ml				ng/ml
Proliferation		328		41		5		37
Ca2+ plateau		510		180		6		28
Ca2+ peak		1,014		344		30		126
% responding cells		1,450		570		13		73

The Ca²⁺ data are from Fig. 5. The proliferation data are from the example shown in Fig. 6 as well as from two other independent experiments.