. Author manuscript; available in PMC: 2008 Jan 24.

Published in final edited form as: Vis Neurosci. 2007 Aug 22;24(4):593–608. doi: 10.1017/S0952523807070575

Table 1.

The effect on adenylate cyclase and PKA activity of the drugs used, and the projected effects on the opening of amacrine cell and ganglion cell hemichannels and their combinations of full channels. Abbreviations: AC, amacrine cell; GC, ganglion cell; Q, quinpirole; H or SCH, SCH23390; S, sulpiride; K or SKF, SKF38393; SPA, Sp-8-CPT-cAMPs; RPA, Rp-8-CPT-cAMPs; OKA, okadaic acid; C, hemichannel closure; O, hemichannel opening; +, activate or increase; −, inhibit or decrease; 0, no effect

	adenylate cyclase		PKA activity		hemichannel p(open)		effect on channel
group(n)	GC (D₂)	AC (D₁)	GC	AC	GC	AC	kGA	kAA	kGG
QH (13)	−	−	−	−	−	+	CO	OO	CC
QK (13)	−	+	−	+	−	−	CC	CC	CC
SH (12)	+	−	+	−	+	+	OO	OO	OO
SK (12)	+	+	+	+	+	−	OC	CC	OO
SKF (11)	0	+	0	+	0	−	C	CC	0
SCH (9)	0	−	0	−	0	+	O	OO	0
SPA (9)	0	0	+	+	+	−	OC	CC	OO
RPA (7)	0	0	−	−	−	+	CO	OO	CC
dopamine (19)	−	+	−	+	−	+	CO	CC	CC
OKA (10)	0	0	?	?	+	−	OC	CC	OO