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. Author manuscript; available in PMC: 2008 Jan 24.
Published in final edited form as: ANS Adv Nurs Sci. 2005;28(4):320–332. doi: 10.1097/00012272-200510000-00004

Table 1.

Selected hypotheses from HIV study

  1. Participants receiving the interventions will have

    1. higher psychosocial functioning as evidenced by

      1. lower perceived stress levels,

      2. more effective coping strategies

      3. less HIV-related psychological distress, and

      4. greater social support

    2. higher quality of life; and

    3. lower stress-related neuroendocrine mediation.

  2. Given that psychoneuroimmunological relationships in the context of HIV infection will be confounded by the immunosuppressive effects of the virus, and controlling for antiretroviral medication regimens, participants receiving interventions will have attenuated immunological dysfunction and better HIV-specific health status, as evidenced by

    1. CD4+, CD8+, and CD57+ lymphocyte levels more closely approximating normal subset distributions;

    2. higher natural killer cell cytotoxic activity;

    3. cellular production of cytokines more closely approximating normal patterns;

    4. higher lymphocyte proliferative function; and

    5. higher HIV-specific health status.