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. 2000 May 1;191(9):1617–1624. doi: 10.1084/jem.191.9.1617

Figure 2.

Figure 2

Schematic representations of HPX42B and NA88-A sequences. Drawings are not to scale. (A) cDNAs; EMBL/GenBank/DDBJ accession nos. AF164963 (NA88-A) and AF068006 (HPX42B). Homologous regions of the two cDNAs are marked in black. For HPX42B cDNA, the open reading frame coding for the homeoprotein (ORF) and the 3′ UTR containing an Alu family member (Alu) are marked. For NA88-A cDNA, the positions of primers used for RT-PCR are marked (400 and 970). (B) Alignment of HPX42B and NA88-A genomic sequences, EMBL/GenBank/DDBJ accession nos. AF164964 and AC006177, respectively. The positions of two HPX42B gene introns are marked, but not their sequences. Dashes represent bases missing in one of the two sequences, and the number of bases concerned is marked. The alternative 3′ splice site of the HPX42B second exon is marked 3′SS. For the NA88-A sequence, the last base shown (g) corresponds to the first base of the cloned cDNA whose sequence is represented in Fig. 2 A. (C) Schematic alignment of the genomic sequences. For the HPX42B gene, exons are marked as boxes, and introns separating them are shown as lines. The alternative 3′ splice site is marked 3′SS. The positions of initiation codons (ATG) and stop codons (*) discussed in the text and boxed in A are marked. The NA88-A gene representation is a composite using information derived from the cosmid and the cDNA as indicated.