Table 2.

Frequency of CD95 Mutations in Human B Cell Subsets; Single-Cell Analysis from Donors II–VII

	Mutations per cell		Mutation frequency
B cell subset; phenotype	5′ region	Exon IX	5′ region	Exon IX
			× 10−4/bp
Naive; IgD+IgM+CD27−	1/48	0/66	0.3	<0.2
GC; CD38+CD77+	12/60	2/45	2.5	0.7
anti-CD95–resistant GC; annexin V–negative, CD38+	4/10	12/22	5.0	7.7
Memory; IgD−CD20+CD27+	6/17	0/33	3.1	<0.4