Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2000 Jun 5;191(11):1987–1998. doi: 10.1084/jem.191.11.1987

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2000 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

CD28 or CTLA-4 antibody fragments can modulate the susceptibility of PHA-stimulated T cells to R5 infection. Freshly isolated CD8-depleted PBMCs were infected with HIV_US-1 (R5) and stimulated with PHA alone or PHA in the presence of 0.1, 1, 3, and 10 μg/ml of anti-CD28 Fab, or PHA in the presence of 0.1, 1, and 10 μg/ml of anti–CTLA-4 F(ab′)₂ fragments. p24 (in ng/ml) was measured in culture supernatants collected at 6 d after infection. Data are representative of three experiments using two different donors.