Fig.4.
Effects of CB1 blockade on the development of conditioned place aversions induced by anandamide after FAAH inhibiton by URB597. Time spent in sec (means ± SEM n=9-11) in the drug-paired compartment during the 15-min pre-test session (open-bars) and the 15-min test session (closed-bars) is shown. Data were analyzed by one-way ANOVA for repeated measures between subjects. 3 mg/kg of AM251 (AM) significantly blocked the development of the conditioned place aversions induced by 3 mg/kg of anandamide (AEA3) after FAAH inhibition by URB597 (URB). (*, P<0.05, as compared with AM+URB+AEA3 test; Newman-Keuls multiple comparison test).