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Voltage dependence of Mg2+ and Ca2+ block of SKCa. (A) Voltage dependence of the apparent Kd of Mg2+ calculated with Eq. 2. Dashed line was fitted to data with Eq. 3, with a Kd at 0 mV of 3 mM and θ (slope factor indicating voltage sensitivity of Kd) = −0.20. (B) Voltage dependence of the apparent Kd of Ca2+ calculated with Eq. 2. Dashed line was fitted to data with Eq. 3, with a Kd at 0 mV of 3 μM and θ = −0.20.
