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. 2008 Jan 28;180(2):325–339. doi: 10.1083/jcb.200705049

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Copyright © 2008, The Rockefeller University Press

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Figure 9. — Model of WB biogenesis. HEX self-assembles (double-headed arrow) in the peroxisome matrix and is recruited to the matrix face of the peroxisome membrane by interaction with WSC. A combination of WSC–WSC and HEX–WSC interactions concentrate WSC in the membrane and promote the production of asymmetrical nascent WBs. WSC complexes can then trigger cortical association, which allows partitioning of the nascent WB and allows segregation of the newly formed organelle into subapical compartments.