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. 2008 Jan 14;180(1):39–50. doi: 10.1083/jcb.200708204

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Copyright © 2008, The Rockefeller University Press

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Figure 2. — Gene positioning during normal differentiation and early mammary tumorigenesis. Indicated gene loci (red) were detected in PFA-fixed, undifferentiated, proliferating 2D culture cells (Day 0) and cells grown for 20 d under 3D growth conditions with 10 d of constitutive activation of ErbB2 (Day 20, ErbB2) or without activation (Day 20 control). Projected stacks of nuclei are shown. Note the difference in scale for Day 0 compared with 3D cultured cells. Bars, 5 μm.