Table 1.

Temporal subfunctionalization frequencies

	Youngest		Oldest
Dataset	f(TSF)	P	f(TSF)	P
alpha	0.015	0	0.108	0.075
cdc15	0.056	0.009	0.092	0.021
elutriation	0.011	0	0.130	0.068
a30	0.010	0	0.117	0.023
a38	0.010	0	0.150	0.205

Frequency of temporal subfunctionalization for the youngest (lowest K_s quartile), and oldest (highest K_s quartile) groups in each of the yeast time-course datasets. Also shown is the P-value for the randomized time-courses. Here, P < 0.025 indicates the actual frequency is significantly below that expected by chance (see Methods – Analysis of yeast data), and P > 0.975 that it is significantly greater.