Figure 2.

IR-induced and MMC-induced γ-H2AX foci in FANCA-mutant primary fibroblast cells compared with gene-corrected controls. (A) After 5 Gy irradiation, GM1309C and gene-corrected control cells were incubated for 2 h at 37°C and stained with anti–γ-H2AX. (B) After 1-h incubation with 3 μM MMC, GM1309C and gene-corrected control cells were washed to remove MMC, further incubated for 48 h at 37°C, and stained with anti–γ-H2AX.