Table 1.

Cross-linking distance constraints used in modeling the c oligomer

Residue pair	Cross-linking properties	Distance constraint range, Å	Final distance, Å
Helix 1 to helix 1
8–8′	Dimer; multimers with 30	4–8	7.2–7.8
10–10′	Dimer	4–11	9.0–10.3
11–11′	Dimer; multimers with 15	4–8	7.2–7.8
15–15′	Dimer; multimers with 11, 26, 30	4–8	6.4–7.1
26–26′	Dimer; multimers with 15, 30	4–8	6.5–6.8
30–30′	Dimer; multimers with 15, 26	4–8	6.8–7.2
14–16′	High-yield multimers	4–8	5.6–5.8
16–18′	High-yield multimers	4–8	4.1–4.3
Helix 1 to helix 2
13–68′	Dimer	4–11	10.1–10.9
14–72′	High-yield multimers	4–8	7.0–7.6
16–68′	Dimer	4–11	10.5–11.0
20–62′	Dimer	4–11	9.2–10.1
21–65′	High-yield multimers	4–8	5.4–5.9
Helix 2 to helix 2
53–53′	Dimer	4–11	11.3–14.8
63–63′	Dimer	4–11	11.9–13.2
66–66′	Dimer	4–11	11.3–11.4
68–71′	Dimer	4–11	11.4–11.5
70–72′	High-yield multimers	4–8	8.1–8.2
74–74′	Dimer at C-terminus	4–14	13.7–14.0
75–75′	Dimer at C terminus	4–14	14.1–14.4
78–78′	Dimer at C terminus	4–14	14.1–14.4