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. 2007 Aug 23;38(2):153–160. doi: 10.1165/rcmb.2007-0173OC

Figure 5.

Figure 5.

Figure 5.

Release of HB-EGF by injured epithelium is necessary for epithelial repair. After mechanical injury monolayers of 1HAEo cells were exposed to a neutralizing anti–HB-EGF antibody (3 μg/ml) or GM6001 (50 μM) in the absence or presence of HB-EGF (20 ng/ml) (A and B, respectively), or 10 μg/ml of CRM197 (C). Corresponding wound areas were determined 0, 8, and 24 hours after wound creation using time-lapse videomicroscopy. Data are mean ± SEM for eight wounds in each group. Error bars are omitted for clarity. *P < 0.05, P < 0.001, §P < 0.01.

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