Table 2.
Parameter | Before rituximab therapy | After rituximab therapy | P |
---|---|---|---|
Total lymphocyte count | 1044 ± 596 | 1734 ± 1535 | NS |
CD4+ lymphocytes | 344 ± 217 | 556 ± 264 | NS |
CD19+ lymphocytes | 243 ± 223 | 74 ± 71 | 0.005 |
Immunoglobulin IgG | 1603 ± 848 | 1596 ± 1055 | NS |
Immunoglobulin IgM | 273 ± 514 | 283 ± 531 | NS |
Upr/cr (mg/mg) | 4.0 ± 3.5 | 0.6 ± 0.6 | 0.001 |
Serum albumin (g/dl) | 2.6 ± 0.7 | 3.5 ± 0.6 | 0.001 |
Scr (mg/dl) | 1.2 ± 0.4 | 0.6 ± 0.2 | 0.001 |
eGFR (ml/min/1.73m2) | 86 ± 32 | 144 ± 37 | 0.0003 |
Corticosteroid dose (mg/m2 per day) | 79 ± 26 | 13 ± 20 | <0.0001 |
SLEDAI-2K score | 47 ± 19 | 25 ± 14 | 0.0004 |