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. 2008 Feb 1;118(3):1027–1039. doi: 10.1172/JCI32020

Figure 7. IL-7 treatment enhances recall CD8 T cell responses following DNA immunization.

Figure 7

C57BL/6 mice were immunized with empty vector pCMV (control) or pCMV-NP. pCMV-NP–immunized mice were treated with IL-7 or PBS between days 14 and 21 after DNA injection and then challenged with LCMV-clone 13 on day 38 after DNA immunization. On day 5 after the LCMV-clone 13 challenge, the number of NP396-specific CD8 T cells in spleen was quantitated by intracellular cytokine staining (A), and LCMV titers in the tissues were assessed by plaque assay (B). Each symbol represents data from an individual mouse.