Table 1.

Endonuclease and RT activities of the mutant R2 proteins normalized to that of wild-type protein

Protein	RT activity	Primer strand cleavage	Nonprimer strand cleavage	TPRT activity
Wild-type	1.00	1.00	1.00	1.00
PA..D	0.82	<0.01	<0.01	<0.01
PE..D	0.78	0.02	<0.01	0.06
YAYD	<0.01	0.92	0.10	<0.01

All values represent the average of three experiments.