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. Author manuscript; available in PMC: 2008 Jan 28.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2007 Dec;48(12):5624–5629. doi: 10.1167/iovs.07-0237

Table 3.

Immunohistochemistry of Lacrimal Gland Inflammation in IL-4-Deficient MRL/MpJ Mice

Mononuclear Inflammatory Cell Staining, %
CD4 CD8 B cells IFN-γ IL-13 CD80 CD86
MRL/MpJ-fas+/fas+-IL-4tm/IL-4tm
 3 63 ± 2 11 ± 4 32 ± 5 70 ± 11 0.6 ± 0.4 3 ± 1 9 ± 2
 5 66 ± 3 13 ± 6 31 ± 6 76 ± 3 0.5 ± 0.2 3 ± 1 14 ± 3
 9 65 ± 10 10 ± 4 10 ± 4 48 ± 5 1.3 ± 0.3 3 ± 2 8 ± 4
 All ages 65 ± 6 12 ± 5 30 ± 5 66 ± 14 0.8 ± 0.5 3 ± 2 11 ± 4
MRL/MpJ-faslpr/faslpr-IL-4tm/IL-4tm
 3 67 ± 11 18 ± 5 14 ± 5 63 ± 10 1.7 ± 1.2 3 ± 1 8 ± 2
 5 36 ± 4 13 ± 3 22 ± 10 71 ± 4 0.7 ± 0.3 4 ± 1 12 ± 3
 All ages 65 ± 8 16 ± 5 18 ± 8 67 ± 8 1.2 ± 0.9 3 ± 1 10 ± 3

Values are mouse ages in months, shown as mean ± SD of 5 animals per age group.