Table 1.

Activation parameters for folding of CI-2, fragment association at atmospheric pressure, and pressure-denatured [C12(1-40)⋅(41-64)]

	ΔCp‡,	ΔH‡,	ΔS‡,	ΔG‡,
	kcal⋅mol−1⋅K−1	kcal⋅mol−1	cal⋅mol⋅K−1	kcal⋅mol−1⋅K−1
CI-2	−0.75 ± 0.06	+12.7 ± 1.2	−7.4 ± 1.2	+14.9
Fragment association	−0.41 ± 0.05	+16.4 ± 0.3	−8.0 ± 0.9	+18.8
Pressure denatured [C12(1-40)⋅(41-64)]	–	+19.1 ± 0.5	−3.1 ± 1.7	+20.2

Thermodynamic parameters at 25°C.