Table 1.

Gene set enrichment analysis results for the gene list tested

Gene set	Comparison
	Old over young cohort			Progesterone receptor-negative over progesterone receptor-positive tumors			ERBB2-negative over ERBB2-positive tumors
	Enrichment score	Nominal P value	FWER P value	Enrichment score	Nominal P value	FWER P value	Enrichment score	Nominal P value	FWER P value
MAPK upregulated	0.44	0.05	0.13	0.28	0.49	0.67	0.28	0.46	0.65
MAPK downregulated	-0.36	0.17	0.4	-0.31	0.33	0.57	0.26	0.26	0.68
Luminal markers	0.31	0.72	0.79	-0.63	0.1	0.15	0.48	0.38	0.57
Proliferation markers	-0.85	0.006	0.011	0.62	0.32	0.38	-0.83	0.01	0.02

Gene sets showing significant enrichment after adjustment for multiple gene set testing (family-wise error rate (FWER) P < 0.05) are presented in bold.