Figure 5.

Principal component analysis of the codon-usage of the hydrogenase and mitochondrial 24/51 kDa modules. While most of the N. ovalis strains exhibit only slight differences in codon-preference, the isolate N. ovalis from the host cockroach P. americana strain Amsterdam has a substantially different codon-usage. In both cases, the bacterial-derived 24 and 51 kDa modules acquired the typical ciliate codon-usage that is not significantly different from the one used for the (nuclear-encoded) mitochondrial modules. Even the top-down distribution shows a complete ameliorisation of the modules.