Figure 3.
Characteristics of heating-activated outward current. (A) A family of currents obtained by voltage steps in 20-mV increments applied at −40 mV and superimposed single exponential fits. The currents were recorded at 32°C. (B) Outward currents evoked by a depolarization pulse of +100 mV applied at −40 mV when temperature was elevated from 24 to 34°C. (C) Activation time constant at different potentials. B and C are obtained from the same cell. The pHp/pHo was 5.5/7.3. The internal buffer was 120 mM Mes.