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. 1997 May 1;109(5):607–617. doi: 10.1085/jgp.109.5.607

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Voltage dependence of macroscopic inactivation properties of glycine mutants. (A) Voltage dependence of macroscopic inactivation. τ_h was determined from single exponential fits to the current decay in macropatch experiments. Average values from 4 to 11 experiments are shown for WT (○), G1484A (•) and G1485A (♦). *The voltage for τ_h values of mutant channels was corrected for differences in the mean midpoints of activation curves relative to WT, to normalize for effects of activation voltage on τ_h. ΔV_1/2 relative to WT in macropatch experiments was −9 mV (G1484A) and +6 mV (G1485A). (B) Steady-state inactivation curves in response to 100-ms pulses. Data are averages of 4-7 two-electrode voltage-clamp experiments (Table I) with WT, (○), G1484A,(•), and G1484V, (▪). Solid lines are least-square fits of the Boltzmann equation to the data.