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. 1997 Mar 1;109(3):313–326. doi: 10.1085/jgp.109.3.313

Figure 2.

Figure 2

Single-channel Ba currents are activated by depolarization. (A) Continuous record (1.7 s) from a patch held at +40 mV from the resting potential shows the typical brief channel openings and two bursts of long openings (right). (B) Capacity- and leak current–subtracted single-channel currents which were elicited by depolarizing voltage steps. (C) Quasimacroscopic currents obtained from averaged, leak-subtracted single-channel current traces elicited by voltage jumps like those in B. Between 8 and 16 records were averaged. (D) Current integrals (charge) from C plotted as a function of the depolarization. Potentials shown along each trace (B and C) indicate the depolarization reached during 70-mV steps of 100 ms duration that were applied from different holding potentials. All potentials are relative to the cells' resting membrane potential. Cell-attached were patches from different cells.