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. 1997 Mar 1;109(3):345–360. doi: 10.1085/jgp.109.3.345

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DNDS inhibits anion exchange by wt AE1 and by E699Q AE1 with similar potency. (A) Effect of increasing concentrations of DNDS on AE1 E699Q-mediated ³⁵SO₄ ²⁻ efflux into Cl⁻ medium. Blockade was reversible. Each trace represents an individual oocyte. Upper trace is water-injected oocyte. (B) DNDS inhibition dose-response curves of wt AE1-mediated ³⁶Cl⁻ efflux and of AE1 E699Q-mediated ³⁵SO₄ ²⁻ efflux. Each of 5 oocytes was exposed for 9 or 12 min to incrementally increasing DNDS concentrations.