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. 1998 Mar 1;111(3):441–450. doi: 10.1085/jgp.111.3.441

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pH dependence of mutant CTX block of wild-type and F425H channels. K31Q block of wild-type (○) and F425H (•) channels and K11Q block of F425H channels (▪). Toxin concentrations of 0.5 μM; currents measured at +40 mV. Dotted line: fit of Eq. 1 to data with K31Q CTX and wild-type channels with K _d and pK _H values of 0.78 μM and 5.4, respectively. Solid line: see discussion. Data values are averages of 3–4 (○), 4–5 (▪), or 5–6 (•); measurements shown with SEM limits.