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. 1998 Apr 1;111(4):555–563. doi: 10.1085/jgp.111.4.555

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Blockage of Kv3.1 currents by Kv3.1-BA antibody. (A) Kv3.1 currents in Kv3.1 stably transfected HEK-293 cells in the absence (HEK/Kv3.1) or presence (+Kv3.1-BA) of Kv3.1-BA. Addition of 250 nM of Kv3.1-BA led to an ∼80% suppression of Kv3.1 currents. (B) Kv3.1-BA blockage is concentration dependent. Data points were taken at 15 min after the addition of antibody. (C and D) Kv3.1-BA has limited effects on Kv1.2 currents in Kv1.2 stably transfected HEK-293 cells. The data are mean ± SD of five to seven experiments.

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