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. 1999 Apr 1;113(4):565–580. doi: 10.1085/jgp.113.4.565

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A voltage clamp waveform in the shape of a ventricular action potential (A) was applied to a HERG expressing CHO-K1 cell at 25°C. The waveform was computed from a published model (Beeler and Reuter, 1977). Superimposed K⁺ current traces measured in 1–3 or 10 mM extracellular Ca²⁺ from a single cell are shown in B. Each trace represents the average of five whole cell voltage clamp sweeps in each condition. Similar results were obtained in two other cells.