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. 2001 Feb 1;117(2):103–118. doi: 10.1085/jgp.117.2.103

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© 2001 The Rockefeller University Press

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).

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Conditions favoring tyrosine phosphorylation do not change single-channel conductance of WT Kir2.1. (A) Traces showing exemplar single-channel currents from cell-attached patches at −100 mV. The arrows point to the closed states and to the open states for control oocytes (left) and for oocytes coinjected with v-Src and treated with PAO (right). (B) Normalized all-points amplitude histograms for exemplar patches. Data from an oocyte injected with Kir2.1 alone are shown as heavy lines, and data from an oocyte injected with Kir2.1 + v-Src and exposed to PAO are shown as light lines.