Figure 3.

Influence of outer vestibule lysines on conductance ratios. A. Currents from a single cell that expressed Kv2.1 channels, recorded with 155 mM external K⁺ (left) and 155 mM Na⁺ (right; the internal solution contained 125 mM NMG⁺). Both currents were evoked by identical stimuli. (B) Currents recorded as in A, except in a cell that expressed Kv2.1 K382V K356G. Note that a slightly longer stimulus duration was used. (C) Conductance ratios for each of the four channels tested as in A and B. The number of cells tested is shown in parentheses.