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Morphology of cauda epididymis in 1-year-old animals. (a) One-year-old w/t cauda epididymis with an abundance of sperm. (b) The lumen of the 1-year-old ArKO mice showing absence of sperm; three of the seven have no elongated spermatids visible in the cauda. (c) The ArKO animals that have undergone spermiogenic arrest show evidence of degenerating germ cells, presumably round spermatids (arrowheads). (Scale bar: 20 μm.)
