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. 2004 Mar;123(3):281–293. doi: 10.1085/jgp.200308986

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Copyright © 2004, The Rockefeller University Press

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Figure 6. — The functionally distinct sites for IVM have different effects on the efficacy of ATP. (A) Perforated-patch whole-cell current traces in response to different concentrations of ATP applied for 2 s, as indicated. Holding potential −50 mV. (B) Concentration-response relationships for ATP in the absence (empty circles) or presence of either 0.2 μM (full circles) or 1.0 μM (full inverted triangles) IVM. Each point represents the average (±SEM) of 6–8 cells. Solid lines are fits to the Hill equation.