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Nucleotide and predicted amino acid sequences of murine and human DIO-1. (A) The bipartite NLS sequence is boxed, and the zinc finger motifs are underlined. (B) Schematic representation of the predicted ORF of murine and human DIO-1. The start and end positions of the amino acids defining the motifs are numbered above. Percentages indicate degree of identity between human and mouse for each domain. Overall similarity is 74%.
