Table 5.

Effect of P-B and BTF-35 on the expression of Bcl-2, Bax, cytochrome C and caspase-3 in experimental and control animals (n = 6)

Group	Treatment	Gradinga
		Bcl-2				Bax				Cytochrome C				Caspase-3
		0	1	2	3	0	1	2	3	0	1	2	3	0	1	2	3
1.	DMBA	0b	0	1	5b	6b	0	0	0	6	0	0	0	5	1	0	0
2.	DMBA+P-B	1c	4	1	0c	0c	0	2	4	0c	1	5c	2	0c	1	3	2
3.	DMBA+BTF-35	1	5c	0	0	0c	0	1	5c	0c	0	6c	4	0c	0	2	4
4.	P-B	5	1	0	0	2	4	0	0	4	2	0	0	3	3	0	0
5.	BTF-35	6	0	0	0	1	5	0	0	3	3	0	0	2	4	0	0
6.	Control	6	0	0	0	2	4	0	0	3	3	0	0	2	4	0	0

a – Expression scored as 0- negative; 1- focal and mildly intense; 2- between one-third and two-third of cells stained moderately, and 3- majority of cells (> two third) stained intensely

b – Significantly different from group 6 by χ²-test (p < 0.05)

c – Significantly different from group 1 by χ²-test (p < 0.05)