Table 2.

Genes directly and indirectly associated with the Reelin signal pathway. The cosine similarities between RELN and genes in the full space and the reduced dimensional space obtained from NMF are also presented. (n/a: not applicable)

Gene	PubMed co-citation		Symbol match		Full space		NMF (k = 3)
	# co-citation	Rank	# match	Rank	cos θ	Rank	cos θ	Rank
Genes directly associated with the Reelin signaling (five genes)
RELN	n/a	-	n/a	-	1.0000	1	1.0000	1
DAB1	9	1	47	1	0.7349	2	0.9964	3
LRP8	2	2	1	7	0.4955	4	0.9854	6
FYN	1	5	4	4	0.2887	9	0.9811	7
VLDLR	2	2	9	2	0.5223	3	0.9463	8
Genes indirectly associated with the Reelin signaling (six genes)
CDK5R1	1	5	0	-	0.2893	7	0.9966	2
CDK5	2	2	3	6	0.2903	6	0.9964	3
CDK5R2	1	5	0	-	0.3228	5	0.9962	5
SRC	1	5	5	3	0.2889	8	0.8433	9
MAPT	0	-	0	-	0.2147	29	0.7630	10
APOE	0	-	0	-	0.2151	28	0.6059	11