Figure 8.

Scatter diagram indicating the range of phenotypic rescue conferred by yS12. Testis sections from adult mice of genotype +/+, Dazl^−/−;TgS12 (−/−;S12), and Dazl^−/− (−/−) were probed with anti-PCNA antibody and scored for the percentage of prophase-positive tubules and mean number of prophase nuclei per positive tubule. Each point represents data from at least 10 (+/+) or 30 tubules (Dazl^−/−;TgS12 and Dazl^−/−) of an individual male. Dazl^−/− individuals were generated in one of two genetic crosses: Dazl^Tm1Hgu/+ × Dazl^Tm1Hgu/+ (1) or Dazl^Tm1Hgu/+;TgS12 × Dazl^Tm1Hgu/+;TgS12 (2). Points corresponding to the Dazl^−/−;TgS12 individuals (a and b) and Dazl^−/− individuals (c and d) represented in Fig. 7 are indicated.